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Propyl Paraben Sodium U.S.P


SYSTEM MANUAL
ISSUE NO : 01
Document No.
Revision No.
Effective date
Page
QAI/Q/03/24
00
1-May-01
1 of 1
PROPYL PARABEN SODIUM U.S.P
 Chemical Name

Sodium Propyl 4-Hydroxybenzoate

 Molecular Formula

C10H11NaO3

 Molecular Weight

202.2

 Structural Formula  
 CAS Number

35285-69-9

 Packing

25 kg, 20 kg ( 4 x 5 kg)

 The Shelf-life

3 years

 Storage conditions and  precautions

Store in a well-closed containers.

 Use Antimicrobial Preservative
 
NO.
Test
Observation
1.
 Description

White powder. Is odorless and hygroscopic.

2.
 Solubility Freely soluble in water; sparingly soluble in alcohol; insoluble in fixed oils.
3.
 Identification

A. Dissolve 0.5 gm in 5 ml of water, acidify with hydrochloric acid; and filter the resulting precipitate. Wash the precipitate with water and, dry it over silica gel for 5.0 hrs: The infrared absorption spectrum of a mineral oil dispersion of it exhibits maxima only at the same wavelengths as that of a similar preparation of usp Propyl Paraben RS. 

B. Ignite about 0.3 gm, cool, and dissolve the residue in about 3 ml of 3N hydrochloric acid. A platinum wire dipped in this solution imparts an intense, persistent yellow colour to a nonluminous flame.

4.
  PH Between 9.5 to 10.5 (1 gm in 1000 ml)
5.
 Water Not more than 5.0 %
6.
 Chlorides Not more than 0.035 %.
7.
 Sulphate

Not more than 0.12%.

8.
 Organic volatile  impurities Method-I < 497 > meets the requirements.
9.
 Assay on dried  basis (As  C10H11NaO3) Not less than 98.5% and not more than 101.5%
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